When Should I Come Off My Antidepressant? Things To Consider

Antidepressants are a type of medication that can help people manage mental health conditions such as depression, anxiety, and obsessive-compulsive disorder (OCD). They work by altering the chemicals in the brain to improve mood and reduce symptoms. However, when it comes to stopping antidepressants, it is important to do so under the guidance of a healthcare professional. Here are some things to consider when deciding when to come off your antidepressant:

Why Are You Considering Stopping Your Antidepressant?

The first step in deciding when to come off your antidepressant is to consider why you want to stop taking it. For example, are you experiencing side effects that are negatively impacting your life? Are you feeling better now and wondering if you still need the medication? Or are you concerned about the long-term effects of taking the drug?

Discussing these concerns with your healthcare professional is essential in determining whether or not it is the right time for you to stop your medication. It is important to remember that once you start taking antidepressants, your body may have become dependent on the medication to maintain your mood, and stopping suddenly could lead to negative outcomes.

How Long Have You Been Taking Your Antidepressant?

The length of time that you have been taking your antidepressant can also be an important factor in deciding when to stop. Most antidepressants take between 4 to 6 weeks to show full effectiveness, and it is generally recommended that patients continue taking the medication for at least 6-12 months to reduce the chances of relapse.

If you have been taking your medication for a year or more, your healthcare professional may advise that you taper off slowly to ensure that your body can adjust to the changes. Abruptly stopping your medication can lead to uncomfortable withdrawal symptoms or increase the risk of relapse.

What Are The Withdrawal Symptoms?

Withdrawal symptoms can occur when you stop taking your antidepressant suddenly or do not taper the medication properly. The symptoms can vary depending on the individual and the medication they are taking, but common withdrawal symptoms include:

  • Anxiety and irritability
  • Dizziness and vertigo
  • Nausea and vomiting
  • Insomnia and nightmares
  • Flu-like symptoms such as headaches or muscle aches

If you are experiencing any withdrawal symptoms, it is important to speak with your healthcare professional to determine the best course of action. They may recommend slowing down the taper process or providing medication to manage the symptoms.

What Are The Risks Of Stopping Your Medication?

Stopping your medication without the supervision of a healthcare professional can increase the risk of relapse. Studies have shown that individuals who stop taking their medication have a higher chance of experiencing a relapse and may need to restart medication to manage their symptoms.

Therefore, before making any decisions about stopping your medication, discuss the risks and benefits with your healthcare professional. They can help you evaluate your current mental health and determine if now is the right time to come off your antidepressant.

What Are The Alternatives To Medication?

If you are concerned about taking medication or want to explore other treatment options, there are alternative therapies available. These therapies can be used in combination with medication or as an alternative to medication. Some of the most common alternatives include:

  • Cognitive-behavioral therapy (CBT): a type of talk therapy that focuses on changing negative thought patterns and behaviors that contribute to mental health conditions.
  • Interpersonal therapy (IPT): a type of talk therapy that focuses on improving communication and relationships with others.
  • Exercise: regular exercise has been shown to have a positive impact on mental health and can be an effective strategy for managing symptoms.
  • Meditation and mindfulness: these practices can help reduce anxiety and improve mood.
  • Diet and nutrition: eating a healthy diet and avoiding certain foods and drinks can improve mental health.

Remember, medication is not the only option for managing mental health conditions. Discussing alternative therapies with your healthcare professional can be an effective option for managing your symptoms.


Deciding when to come off your antidepressant is a decision that should be made in consultation with your healthcare professional. It is important to consider why you want to stop taking the medication, how long you have been taking it, and the potential withdrawal symptoms and risks of stopping suddenly. Alternative therapies can also be effective options for managing mental health conditions.

If you are considering coming off your antidepressant, speak with your healthcare professional to develop a plan that works for you.


FAQs: When Should I Come Off My Antidepressant Things To Consider

1. What are the common side effects of stopping antidepressants?

Common side effects of stopping antidepressants may include withdrawal symptoms such as dizziness, nausea, irritability, anxiety, insomnia, and flu-like symptoms. However, these symptoms can vary depending on the type of antidepressant, the dosage, and how long you have been taking the medication. It is important to consult with your healthcare provider before stopping any medication.

2. How do I know when it’s time to stop taking my antidepressant?

Deciding when to come off an antidepressant medication can be a complex decision that should be made in consultation with your healthcare provider. They will consider factors such as your mental health status, symptoms, medication history, and potential risks and benefits of discontinuing the medication. Additionally, your healthcare provider may recommend gradually reducing your dosage over a period of weeks or months to minimize the risk of withdrawal symptoms.

3. What can I expect during the process of coming off my antidepressant?

The process of coming off an antidepressant can be different for each person. Some people may experience few or no withdrawal symptoms while others may experience more severe symptoms. It is important to work with your healthcare provider to develop a personalized tapering plan that is safe and effective for you. Additionally, it is important to monitor your mental health status closely during the tapering process, as symptoms can worsen or recur when the medication is discontinued.


1. American Psychiatric Association. (2010). Practice guideline for the treatment of patients with major depressive disorder. American Psychiatric Association. https://psychiatryonline.org/pb/assets/raw/sitewide/practice_guidelines/guidelines/mdd.pdf

2. Fava, G. A., Gatti, A., Belaise, C., Guidi, J., & Offidani, E. (2015). Withdrawal symptoms after selective serotonin reuptake inhibitor discontinuation: A systematic review. Psychotherapy and Psychosomatics, 84(2), 72-81. https://doi.org/10.1159/000370338

3. Royal Australian and New Zealand College of Psychiatrists. (2018). Clinical practice guideline for mood disorders. RANZCP. https://www.ranzcp.org/files/resources/college_statements_and_guidelines/practice_guidelines/ranzcp-mood-disorders-guideline-(apr-2018).aspx