Some People Feel Worse On Antidepressants Like Cymbalta

Antidepressants are prescribed to millions of people each year. In Australia alone, approximately 3 million people take antidepressants, according to the latest available data. While antidepressants have been effective in treating depression and other mental health disorders, they may not work for everyone.

What is Cymbalta?

Cymbalta (duloxetine hydrochloride) is an antidepressant medication that is used to treat depression, anxiety, and other mental health disorders. It belongs to a class of drugs called serotonin-norepinephrine reuptake inhibitors (SNRIs) that work by increasing the levels of serotonin and norepinephrine in the brain.

Cymbalta is also used to treat fibromyalgia and chronic pain, as it helps to reduce nerve pain by blocking the absorption of certain chemicals in the brain.

Why do Some People Feel Worse on Antidepressants?

While antidepressants like Cymbalta can be effective in treating depression and other mental health disorders, some people may experience negative side effects or feel worse while taking them.

There are several reasons why some people may not respond well to antidepressant medication:

1. Incorrect Diagnosis

One of the primary reasons that antidepressants may not work for someone is that they have been misdiagnosed. It’s important to undergo a proper psychiatric evaluation to determine the best course of action for treating your symptoms. If you’ve been prescribed antidepressants but aren’t feeling any better, it may be worth getting a second opinion to rule out other underlying conditions such as bipolar disorder, anxiety disorder, or post-traumatic stress disorder.

2. Genetic Variations

Individuals may react differently to medication due to their unique genetic makeup. Some people have a genetic variation that affects the way their body processes certain medications. This can result in slower or faster metabolism, which may lead to a buildup of the medication in their system or quick elimination of the medication from their system. This can cause unexpected side effects or altered effectiveness of the medication.

3. Dosing and Timing

The dosage and timing of medication can also play a role in how well it works. Some people may need an adjusted dosage or different timing to achieve the desired effects. It’s important to work with your doctor to establish a treatment plan that works best for you.

4. Other Medications or Substances

Combining antidepressants with other medications or substances can lead to negative side effects or diminish the effectiveness of the medication. It’s important to let your doctor know about all the medications and substances you’re taking, including over-the-counter medications, to avoid any potential interactions.

What Are Common Side Effects of Cymbalta?

Like all medications, Cymbalta can cause side effects in some people. Common side effects of Cymbalta include:

  • Drowsiness or fatigue
  • Dizziness
  • Nausea
  • Dry mouth
  • Headache
  • Constipation
  • Increased sweating
  • Decreased appetite
  • Insomnia

In rare cases, Cymbalta can cause more serious side effects, such as:

  • Suicidal thoughts or behaviours
  • Increased heart rate or blood pressure
  • Bleeding or bruising
  • Muscle pain or weakness
  • Seizures

If you experience any of these more serious side effects while taking Cymbalta, you should seek medical attention immediately.

What Should You Do If Antidepressants Aren’t Working for You?

If you’ve been taking antidepressants like Cymbalta and haven’t experienced any improvement in your symptoms, there are several options available to you:

1. Talk to Your Doctor

The first step is to talk to your doctor about your concerns. They may recommend a different dosage, timing, or medication altogether. Your doctor may also want to perform additional testing or evaluations to determine if there are any underlying medical conditions contributing to your symptoms.

2. Therapy

Talking to a mental health professional can also be helpful in managing symptoms of depression and other mental health disorders. Therapy can provide you with coping strategies and support to manage your symptoms more effectively.

3. Lifestyle Changes

Exercise, a healthy diet, and stress management techniques such as meditation or yoga can be helpful in managing symptoms of depression and anxiety. Incorporating these changes into your daily routine can have a positive impact on your overall well-being.

4. Consider TMS Therapy or ECT

If traditional antidepressants haven’t worked for you, your doctor might suggest other treatment options such as transcranial magnetic stimulation (TMS) therapy or electroconvulsive therapy (ECT). These therapies use magnetic fields or electric currents to stimulate specific areas of the brain that are responsible for regulating mood.

Conclusion

Antidepressants like Cymbalta can be effective in treating depression, anxiety, and other mental health disorders. However, they may not work for everyone. If you’re experiencing negative side effects or not seeing any improvement in your symptoms, it’s important to talk to your doctor about alternative treatment options. With the right combination of medication, therapy, and lifestyle changes, you can manage your symptoms effectively and improve your overall quality of life.

FAQs

FAQs: Some People Feel Worse On Antidepressants Like Cymbalta

1. Why do some people feel worse when taking antidepressants like Cymbalta?

Antidepressants like Cymbalta work by changing the levels of certain chemicals in the brain, such as serotonin and norepinephrine. However, some people may have a difficult time adjusting to these changes and experience side effects that cause them to feel worse. These side effects can include increased anxiety, nausea, dizziness, and insomnia.

2. Is it normal to feel worse before feeling better when taking antidepressants like Cymbalta?

Yes, it is common for people to experience worsening symptoms during the first few weeks of taking antidepressants like Cymbalta. This is because the brain is adjusting to the changes caused by the medication, and it may take some time before the person feels the full benefits of the medication. It’s important to talk to your doctor about any side effects or symptoms you are experiencing while taking antidepressants.

3. What should I do if I feel worse on antidepressants like Cymbalta?

If you are experiencing side effects or feel worse while taking antidepressants like Cymbalta, it’s important to talk to your doctor. They may be able to adjust the dosage or switch you to a different medication that may work better for you. It’s important not to stop taking antidepressants without consulting your doctor, as this can lead to withdrawal symptoms and could be dangerous.


References

1. Barrett, J. S., L citra, M. J., & Blier, P. (2009). Benefits and risks of Cymbalta treatment for major depressive disorder. Drug Safety, 32(9), 735-745.

2. Molero, Y., Lichtenstein, P., Hedman, E., Forsell, Y., & Sjöqvist, F. (2014). Antidepressant treatment and risk of mania: a nationwide population-based study. Bipolar Disorders, 16(4), 394-404.

3. Pérez, V., Gilaberte, I., Faries, D., Alvarez, E., & Artigas, F. (2011). Randomised, placebo-controlled trial of the efficacy and tolerability of duloxetine 60 mg once daily in the treatment of major depressive disorder. Journal of psychopharmacology, 25(6), 837-846.