Medical Marijuana for Anxiety and Depression: Is it Really Effective?

Medical marijuana has been a controversial topic in Australia and around the world. However, with the growing acceptance of medical cannabis, more and more studies are being conducted on the potential benefits of cannabis for treating various health conditions, including anxiety and depression.

The Connection between Anxiety, Depression, and Medical Cannabis

Anxiety and depression are two of the most common mental health disorders that affect millions of people worldwide. While there are several pharmaceutical medications available to treat these conditions, such as selective serotonin reuptake inhibitors (SSRIs), benzodiazepines, and tricyclic antidepressants, the side effects and long-term use of these drugs can be concerning for some individuals.

That’s why researchers are looking at alternatives such as medical marijuana to determine if it can provide a more natural approach to treating anxiety and depression.

What is Medical Marijuana?

Medical marijuana refers to the use of the cannabis plant, specifically the cannabinoids within it, to treat different medical conditions. Unlike recreational marijuana, which is used for its psychoactive effects, medical cannabis is used for its therapeutic properties.

Medical marijuana contains two main active components: tetrahydrocannabinol (THC) and cannabidiol (CBD). THC is responsible for producing the psychoactive effects of marijuana, while CBD does not produce any psychoactive effects and is known for its potential health benefits.

How Does Medical Marijuana Help with Anxiety and Depression?

Researchers believe that medical marijuana can help with anxiety and depression by interacting with the endocannabinoid system (ECS) within our body. The ECS is a complex system of receptors and neurotransmitters that helps regulate a variety of physiological functions in the body, including mood, appetite, sleep, and pain sensation.

Studies have shown that the cannabinoids in medical marijuana can activate these receptors, which can have a positive effect on mood and anxiety levels. THC, for example, can produce feelings of euphoria and relaxation, which can help ease anxiety and depression symptoms. CBD, on the other hand, can help regulate serotonin levels in the brain, which is the neurotransmitter responsible for regulating mood, social behavior, and sleep.

The Benefits of Medical Marijuana for Anxiety and Depression

Several studies have shown that medical marijuana can have a positive effect on anxiety and depression symptoms.

One study conducted by researchers at Washington State University found that using medical marijuana reduced the symptoms of depression by an average of 50 percent. Another study conducted by Harvard Medical School and McLean Hospital found that medical marijuana reduced anxiety symptoms in patients with social anxiety disorder.

Medical marijuana can also be beneficial for individuals who have not had success with traditional medications. Several patients with treatment-resistant depression have reported significant improvements in their symptoms after using medical marijuana.

The Risks of Medical Marijuana for Anxiety and Depression

While medical marijuana shows promise in treating anxiety and depression, it is not without its risks.

One potential risk is the psychoactive effects of THC, which can cause feelings of paranoia and anxiety in some individuals. It’s essential to understand the risks of THC before using medical marijuana as a treatment for anxiety and depression.

Another potential risk is the lack of regulation in the medical marijuana industry. Medical marijuana is not regulated by the Food and Drug Administration (FDA) in the same way that pharmaceutical medications are. This means that the potency, purity, and consistency of medical marijuana products can vary significantly, making it challenging to determine the optimal doses for treating anxiety and depression.

Final Thoughts

Overall, medical marijuana shows promise in treating anxiety and depression. Still, more research is needed to determine the optimal doses for specific conditions and to understand the long-term effects of using medical marijuana.

As with any treatment, it’s important to consult with a healthcare professional before using medical marijuana. Patients should also understand the potential risks and benefits of using medical marijuana and be prepared to make an informed decision.


FAQs about Medical Marijuana for Anxiety and Depression

What is medical marijuana?

Medical marijuana is a plant-based medicine that has been legalized in some countries, including Australia, for its therapeutic purposes. It contains compounds that provide relief from various symptoms, including anxiety and depression. Medical professionals can prescribe marijuana as a form of treatment to patients who suffer from these mental health conditions.

How does medical marijuana help with anxiety and depression?

Medical marijuana contains cannabinoids, a compound that interacts with the human body’s endocannabinoid system. This system may regulate mood, sleep, appetite, and pain sensations. In patients with anxiety and depression, medical marijuana may reduce symptoms by improving neurotransmitter signaling in the brain, promoting relaxation and calmness, and boosting one’s overall sense of well-being.

What are the potential side effects of using medical marijuana for anxiety and depression?

As with any medication, medical marijuana may cause some side effects, such as dry mouth, nausea, dizziness, and temporary changes in heart rate and blood pressure. It may also interact with other medications a patient is taking, so it is essential to disclose all current medications to your healthcare provider before starting treatment with medical marijuana. Like any other medication, medical marijuana should only be taken under the guidance of a licensed medical professional.


1. Turna, J., Simpson, W., Patterson, B., Lucas, P., & Van Ameringen, M. (2019). Cannabis use behaviors and prevalence of anxiety and depressive symptoms in a cohort of Canadian medicinal cannabis users. Journal of psychiatric research, 115, 90-95. [doi:10.1016/j.jpsychires.2019.05.015]

2. Cuttler, C., Spradlin, A., & McLaughlin, R. J. (2018). A naturalistic examination of the perceived effects of cannabis on negative affect. Journal of affective disorders, 235, 198-205. [doi:10.1016/j.jad.2018.04.054]

3. Sarris, J., Sinclair, J., & Karamacoska, D. (2019). Medicinal cannabis for psychiatric disorders: a clinically-focused systematic review. BMC psychiatry, 19(1), 1-31. [doi:10.1186/s12888-018-1962-2]