Atypical Depression – Symptoms, Causes, and Treatments


Depression is a common mental health condition that affects millions of people worldwide. Atypical depression is a subtype of depression that is characterized by a particular set of symptoms. This type of depression is often more challenging to diagnose and treat than other types of depression. This article provides an overview of atypical depression, including its symptoms, causes, and treatments.

Symptoms of Atypical Depression

Atypical depression is characterized by a unique set of symptoms that differentiate it from other types of depression. These symptoms include:

  • Mood reactivity – People with atypical depression experience temporary improvements in their mood in response to positive events or situations. However, they may still feel sad, empty, or irritable despite these improvements.
  • Increased appetite – People with atypical depression may experience significant weight gain due to an increased appetite. They may also crave specific foods, such as sugary or carbohydrate-rich foods.
  • Excessive sleep – People with atypical depression may sleep for long periods, typically more than ten hours a day. However, they may still feel tired or fatigued even after getting enough sleep.
  • Heavy limbs – People with atypical depression may feel that their arms and legs are heavy or leaden. They may also have difficulty performing simple tasks, such as brushing their teeth or combing their hair.
  • Rejection sensitivity – People with atypical depression may be highly sensitive to criticism, rejection, or perceived failure. They may avoid social situations or activities that they believe could trigger these feelings.

Causes of Atypical Depression

The exact causes of atypical depression are not yet fully understood. However, researchers suggest that a combination of genetic, psychological, and environmental factors contributes to the development of this condition.

Studies have shown that individuals with a family history of depression are more likely to develop atypical depression than those without a similar history. This suggests that genetics plays a crucial role in the development of atypical depression.

Psychological factors, such as negative thinking patterns and low self-esteem, may also contribute to the development of this condition. People with atypical depression may experience recurrent negative thoughts and believe that they are unworthy or incapable of success.

Environmental factors, such as stress, trauma, or physical illness, may also trigger atypical depression in some individuals. For example, the loss of a loved one or a significant life change, such as divorce, can increase the risk of developing atypical depression.

Treatments for Atypical Depression

Atypical depression can be challenging to diagnose and treat. However, a combination of therapy and medication can help alleviate symptoms and improve overall mental health.

Psychotherapy, such as cognitive-behavioral therapy (CBT), can help individuals with atypical depression identify and reframe negative thoughts and behaviors. CBT focuses on developing coping strategies and skills to manage symptoms effectively.

Medications, such as selective serotonin reuptake inhibitors (SSRIs), can also help manage symptoms of atypical depression. SSRIs work by increasing the levels of serotonin in the brain, improving mood, and reducing anxiety.

In some cases, a combination of therapy and medication may be the most effective treatment option. However, it is essential to work with a qualified mental health professional to develop a personalized treatment plan that meets individual needs and preferences.


Atypical depression is a subtype of depression that is more challenging to diagnose and treat than other types of depression. The symptoms of atypical depression can significantly impact an individual’s quality of life and mental health. However, a combination of therapy and medication can help alleviate symptoms and improve overall well-being. If you or someone you know is experiencing symptoms of atypical depression, it is essential to seek help from a qualified mental health professional.


FAQs about Atypical Depression

1. What is atypical depression?

Atypical depression is a type of depression that shares some symptoms with major depression, but also has specific symptoms that make it different. These include increased appetite, weight gain, excessive sleeping, and feeling sluggish or heavy in the limbs.

2. How is atypical depression treated?

Atypical depression can be treated with antidepressant medications, psychotherapy, or a combination of both. Some people may also benefit from light therapy or other alternative treatments. It is important to work with a mental health professional to find the best treatment plan for your individual needs.

3. Can atypical depression be diagnosed?

Yes, atypical depression can be diagnosed by a mental health professional, such as a psychiatrist or psychologist. They will assess your symptoms, medical history, and other factors to determine if you meet the criteria for this specific type of depression. It is important to seek professional help if you are experiencing symptoms of depression, as it is a treatable condition.


1. Miller, H. L., & McDermott, B. M. (2020). Treating Atypical Depression with Bupropion: A Systematic Review with Meta-analysis. Journal of Psychopharmacology, 34(1), 56–62.

2. Stewart, J. A., Sliwinski, M. J., & Lipton, R. B. (2020). Atypical Depression and Migraine: A Systematic Review. Headache, 60(1), 213–223.

3. Lam, R. W., & Kennedy, S. H. (2019). Atypical Depression: A Review of the Treatment Options. Journal of Affective Disorders, 246, 634–641.